Metabolic Investigation of diabetes mellitus and hepatocutaneous syndrome
Dr. Loftus and Dr. Bethany Cummings are seeking samples from dogs with Hepatocutaneous Syndrome, with or without Diabetes Mellitus, dogs with Diabetes Mellitus (that do not have HCS), and healthy control dogs. We ask that medical records be provided and any dogs enrolled have a CBC and Chemistry performed (and results provided to us) within 3 months of submission. We are also banking urine samples (ideally frozen) that can be sent to the address below along with other samples. Please also fill out the electronic survey we've created.
How do i know a patient is eligible?
If the patient has a liver or skin biopsy that supports a diagnosis of HCS, or if the dog has skin lesions typical of superficial necrolytic dermatitis, liver ultrasound, and amino acid profile results compatible with the syndrome they likely qualify. If you're still unsure, please contact Dr. Loftus.
Do the fasting and post-prandial (post-meal) samples need to be from the same day?
Yes, as the hormones we are measuring can fluctuate somewhat from day to day, we need samples that are paired.
How should I store samples before shipping to your lab?
It is best to freeze plasma and urine and ship on dry ice if possible (if not cold packs are acceptable). The EDTA whole blood should be refrigerated.
Are there certain days that are best to ship samples?
Yes, shipping samples Monday through Wednesday best assures they will arrive by Friday and we'll be able to put them directly into cold storage. Please contact us before shipping so we can provide a label and make sure that staff will be available to receive the sample.
Download our client consent forms below